Need help to run 2x8 gb ram DDR3 1600mhz on my gigabyte motherboard

[AK82]

Dear experts,

I have gigabyte motherboard EP45T UD3LR F5 bios with running ram 2x2 gb with 533Mhz. Now i bought 2x8 gb DDR3 1600mhz. Kindly help me what setting should i do to make them running. When i replace my old rams with new one system not start only beep sound.

Thanks in advance

[ephe]

That board only takes 4GB modules